Name | 4-Aminonicotinic acid |
Synonyms | H-4ANIC-OH AURORA KA-2553 AKOS BBS-00001375 IFLAB-BB F1957-0006 RARECHEM AL BE 1386 4-Aminonicotinic acid 4-Amino Nicotinic Acid 4-AMINO-3-CARBOXYPYRIDINE 4-Amino Nicotinic Acid Methyl 4-amino-3-pyridinecarboxylic acid 4-Aminopyridine-3-carboxylic acid 4-AMINO-3-PYRIDINECARBOXYLIC ACID |
CAS | 7418-65-7 |
EINECS | 628-821-5 |
InChI | InChI=1/C6H6N2O2/c7-5-1-2-8-3-4(5)6(9)10/h1-3H,(H2,7,8)(H,9,10) |
Molecular Formula | C6H6N2O2 |
Molar Mass | 138.12 |
Density | 1.3471 (rough estimate) |
Melting Point | 307-312°C |
Boling Point | 253.51°C (rough estimate) |
Flash Point | 193.194°C |
Solubility | Soluble in aqueous acid and base. |
Vapor Presure | 0mmHg at 25°C |
Appearance | Bright yellow crystal |
Color | Cream to yellow |
pKa | 2.94±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.5100 (estimate) |
MDL | MFCD00234183 |
Use | 4-Aminonicotinic acid has been used in the preparation of 2-methyl-pyrido-oxazine. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
TSCA | N |
HS Code | 29333990 |
Hazard Class | IRRITANT |
Introduction | 4-aminopyridine-3-carboxylic acid (δ) is widely used as an intermediate in the synthesis of drugs. Such as 4-aminopyridine-3-carboxylic acid as raw material synthesis of antibacterial, anti-inflammatory drug naphthyridinone. Therefore, it is of great significance to develop a simple, efficient and safe synthesis process. |
Application | 4-aminopyridine-3-carboxylic acid is a nitrogen-heterocyclic nitrogen-complexing chelator, the nitrogen atom on the pyridine ring has a strong coordination function, and can form a stable complex with metal ions, which is suitable for selective separation and recovery of heavy metal ions in solution, hydrometallurgy and other aspects of a wide range of applications. |