4-amino-3-pyridinecarboxylic acid

Name	4-Aminonicotinic acid
Synonyms	H-4ANIC-OH AURORA KA-2553 AKOS BBS-00001375 IFLAB-BB F1957-0006 RARECHEM AL BE 1386 4-Aminonicotinic acid 4-Amino Nicotinic Acid 4-AMINO-3-CARBOXYPYRIDINE 4-Amino Nicotinic Acid Methyl 4-amino-3-pyridinecarboxylic acid 4-Aminopyridine-3-carboxylic acid 4-AMINO-3-PYRIDINECARBOXYLIC ACID
CAS	7418-65-7
EINECS	628-821-5
InChI	InChI=1/C6H6N2O2/c7-5-1-2-8-3-4(5)6(9)10/h1-3H,(H2,7,8)(H,9,10)

Molecular Formula	C6H6N2O2
Molar Mass	138.12
Density	1.3471 (rough estimate)
Melting Point	307-312°C
Boling Point	253.51°C (rough estimate)
Flash Point	193.194°C
Solubility	Soluble in aqueous acid and base.
Vapor Presure	0mmHg at 25°C
Appearance	Bright yellow crystal
Color	Cream to yellow
pKa	2.94±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.5100 (estimate)
MDL	MFCD00234183
Use	4-Aminonicotinic acid has been used in the preparation of 2-methyl-pyrido-oxazine.

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
TSCA	N
HS Code	29333990
Hazard Class	IRRITANT

Introduction	4-aminopyridine-3-carboxylic acid (δ) is widely used as an intermediate in the synthesis of drugs. Such as 4-aminopyridine-3-carboxylic acid as raw material synthesis of antibacterial, anti-inflammatory drug naphthyridinone. Therefore, it is of great significance to develop a simple, efficient and safe synthesis process.
Application	4-aminopyridine-3-carboxylic acid is a nitrogen-heterocyclic nitrogen-complexing chelator, the nitrogen atom on the pyridine ring has a strong coordination function, and can form a stable complex with metal ions, which is suitable for selective separation and recovery of heavy metal ions in solution, hydrometallurgy and other aspects of a wide range of applications.

Last Update：2024-04-09 15:16:52

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4-amino-3-pyridinecarboxylic acid

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